Obesity and Psychiatric Disorders


Obesity is associated with a 25% increase in the risk of mood and anxiety disorders, as well as a 25% reduction in the risk of substance use disorders. Because the association between obesity and mood disorder differs by demographic group, social or cultural factors may affect or mitigate the relationship. These findings suggest that obesity-related metabolic abnormalities play a role in the aetiology of psychotic diseases, and that metabolic status should be investigated as a phenotypic intermediate in psychotic disorders.


  • Neuroprogression
  • Inflammation
  • Obesity
  • Oxidative stress

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